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    Home / Smart MES / Medical Devices
    Industry Solution

    Medical Devices · ISO 13485 / 21 CFR Part 11

    Medical devices is one of manufacturing's most heavily regulated fields: the ISO 13485 system, FDA 21 CFR Part 11 electronic signatures / audit trail, UDI unique identification, the CAPA workflow, and sterilization validation. SBK MES turns these compliance requirements into out-of-the-box capabilities.

    ISO
    13485 Compliance
    21 CFR
    Part 11 Met
    UDI
    Unique Identification
    Industry Pain Points vs. MES Solutions

    6 Typical Challenges of Medical-Device Factories

    High compliance demands and high cost of failure require every step to be traceable and provable

    📝 Pain Point 1: Electronic Signatures

    21 CFR Part 11 requires electronic signatures on all key operations → electronic signatures across all modules + two-factor authentication

    📜 Pain Point 2: Audit Trail

    Every data change must trace the who / when / why → full-field audit logs, never deleted

    📱 Pain Point 3: UDI Identification

    FDA requires UDI unique identification for devices → DI + PI dual-segment coding + auto-marking and GUDID upload

    🔁 Pain Point 4: CAPA Workflow

    Deviations / complaints / recalls must go through CAPA → templated CAPA workflow + tracking + effectiveness verification

    ⚗ Pain Point 5: Sterilization Validation

    Each sterilization batch needs parameters + chemical indicator + biological indicator → sterilization parameters auto-recorded + three-way validation

    📚 Pain Point 6: DHR Batch Records

    Each batch must have complete DHR documentation → MES auto-generates the DHR, including full-operation parameters / inspection / signatures

    mes.shangbangke.com/medical/audit21 CFR Part 11
    ES
    E-Sign Audit Trail — Batch BR-0512
    CSVE-sign
    TimeAction / valuesBySign
    14:02Dosing verify 200kgLiSigned
    14:18Temp 119→121℃WangSigned
    15:05QA release reviewZhangPending
    —ALCOA+ integrity checkSystemPass

    21 CFR Part 11 Electronic Signatures + Audit Trail

    FDA 21 CFR Part 11 is the compliance ceiling of the medical / pharma industry: electronic records and signatures must carry the same legal force as paper signatures, and all changes must be traceable. SBK MES makes this compliance a built-in capability, with no extra integration needed.

    • Electronic signatures: username + password + action binding, non-repudiable
    • Audit trail: each change records who / when / before & after values / reason
    • System validation (CSV): IQ / OQ / PQ documentation included
    • Data integrity ALCOA+: original / traceable / contemporaneous
    mes.shangbangke.com/medical/udiUDI submit
    UD
    UDI Identifier — Single-Use Catheter
    MarkSubmit GUDID
    (01)06901234567890
    LOT-2605-08
    SN-000128
    (11)260512
    (17)280511
    GUDID submitted

    UDI Unique Identification: From Marking to GUDID Submission

    FDA requires devices to carry a UDI unique identifier, comprising the DI (device identifier) + PI (production identifier). SBK MES closes the full UDI loop — generation / marking / database submission — including integration with the GUDID / EU EUDAMED databases.

    • DI portion: auto-pulled from the device-model dictionary
    • PI portion: lot number + serial number + production date + expiry
    • UDI codes auto-printed onto packaging and the device itself
    • UDI data auto-submitted to GUDID / EUDAMED
    mes.shangbangke.com/medical/capaISO 13485
    CA
    CAPA Workflow — CAPA-0231
    RCASubmit
    Deviation
    Logged + disposition
    Root cause
    5 Why confirmed
    CAPA action
    Implement 66%
    Verify
    3 batches tracked

    Each step signed · retrievable for audit

    CAPA Workflow: From Deviation to Effectiveness Verification

    ISO 13485 requires all deviations / complaints / nonconformities to go through CAPA: corrective actions + preventive actions + effectiveness verification. SBK MES templates the CAPA workflow, with every step traceable and signed, to the auditor's satisfaction.

    • Deviation logging: symptom / time / impact scope / urgent disposition
    • Root-cause analysis (RCA): fishbone / 5 Why / 8D tools
    • Corrective & preventive actions: feasibility assessment + implementation plan
    • Effectiveness verification: tracked and verified over N batches
    Use Cases

    In Action Across Medical-Device Sub-Sectors

    Sterile Consumables

    Syringes / catheters / surgical kits, with strong traceability + sterilization validation + UDI

    Implantable Devices

    Bone screws / cardiac stents — Class III devices with the strictest traceability down to each SN

    IVD In-Vitro Diagnostic Reagents

    Reagent kit batches bound to standard curves, with expiry + storage/transport temperature traced throughout

    Medical Equipment Assembly

    Large medical equipment in ETO mode, with installation & commissioning reports + integrated after-sales repair

    Related Features

    Core Modules Behind the Medical Solution

    These MES modules together form the medical-device solution

    🔍 Product Traceability

    UDI and SN traceability

    📈 SPC Statistical Process Control

    Key-parameter CPK monitoring

    📋 Office Integration

    Electronic signatures via OA approval

    ✅ First / Patrol / Final Inspection

    Digitized three-check + audit trail

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    Try the Medical-Device MES Solution Today

    Sign up to explore ISO 13485 / 21 CFR Part 11 compliance capabilities for free, or book a consultant demo

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